Mattia Bramini

Affiliated Researcher

Research Lines



Via Morego, 30
+39 010 555 8491

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2010 - 2014 PhD in BioNano Interactions at the Centre for BioNano Interactions (CBNI), School of Chemistry and Chemical Biology, University College Dublin, Ireland

2007 - 2009 MSc Degree in Medical and Pharmaceutical Biotechnology, Università di Modena e Reggio Emilia

2004 - 2007 BSc Degree in Biotechnology, Università di Modena e Reggio Emilia

IIT Publications

  • 2021
  • Moschetta M., Lee J. Y., Rodrigues J., Podestà A., Varvicchio O., Son J., Lee Y., Kim K., Lee G. H., Benfenati F.iit, Bramini M.iit, Capasso A.

    Hydrogenated Graphene Improves Neuronal Network Maturation and Excitatory Transmission

    Advanced Biology
  • Liessi N.iit, Maragliano L.iit, Castagnola V.iit, Bramini M.iit, Benfenati F.iit, Armirotti A.iit

    Isobaric Labeling Proteomics Allows a High-Throughput Investigation of Protein Corona Orientation

    Analytical Chemistry, vol. 93, (no. 2), pp. 784-791
  • 2020
  • Munteanu R.-E., Moreno P.S., Bramini M.iit, Gaspar S.

    2D materials in electrochemical sensors for in vitro or in vivo use

    Analytical and Bioanalytical Chemistry
  • Candotto Carniel F., Fortuna L., Nepi M., Cai G., Del Casino C., Adami G., Bramini M.iit, Bosi S., Flahaut E., Martin C., Vazquez E., Prato M., Tretiach M.

    Beyond graphene oxide acidity: Novel insights into graphene related materials effects on the sexual reproduction of seed plants

    Journal of Hazardous Materials, vol. 393
  • Capasso A., Rodrigues J., Moschetta M.iit, Buonocore F., Faggio G., Messina G., Kim M.J., Kwon J., Placidi E., Benfenati F.iit, Bramini M.iit, Lee G.-H., Lisi N.

    Interactions between Primary Neurons and Graphene Films with Different Structure and Electrical Conductivity

    Advanced Functional Materials
  • Paterno G.M.iit, Colombo E.iit, Vurro V.iit, Lodola F.iit, Cimo S., Sesti V., Molotokaite E.iit, Bramini M.iit, Ganzer L., Fazzi D., D'Andrea C.iit, Benfenati F.iit, Bertarelli C., Lanzani G.iit

    Membrane Environment Enables Ultrafast Isomerization of Amphiphilic Azobenzene

    Advanced Science, vol. 7, (no. 8)
  • DiFrancesco M.L.iit, Lodola F.iit, Colombo E.iit, Maragliano L.iit, Bramini M.iit, Paterno G.M.iit, Baldelli P., Serra M.D., Lunelli L., Marchioretto M., Grasselli G.iit, Cimo S.iit, Colella L., Fazzi D., Ortica F., Vurro V.iit, Eleftheriou C.G.iit, Shmal D.iit, Maya-Vetencourt J.F.iit, Bertarelli C.iit, Lanzani G.iit, Benfenati F.iit

    Neuronal firing modulation by a membrane-targeted photoswitch

    Nature Nanotechnology, vol. 15, (no. 4), pp. 296-306
  • Marquitan M., Ruff A., Bramini M.iit, Herlitze S., Mark M.D., Schuhmann W.

    Polymer/enzyme-modified HF-etched carbon nanoelectrodes for single-cell analysis

    Bioelectrochemistry, vol. 133
  • Maya-Vetencourt J.F.iit, Manfredi G.iit, Mete M., Colombo E.iit, Bramini M.iit, Di Marco S.iit, Shmal D.iit, Mantero G.iit, Dipalo M.iit, Rocchi A.iit, DiFrancesco M.L.iit, Papaleo E.D.iit, Russo A., Barsotti J.iit, Eleftheriou C.iit, Di Maria F., Cossu V., Piazza F., Emionite L., Ticconi F., Marini C., Sambuceti G., Pertile G., Lanzani G.iit, Benfenati F.iit

    Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy

    Nature Nanotechnology, vol. 15, (no. 8), pp. 698-708
  • 2019
  • Bramini M.iit, Chiacchiaretta M.iit, Armirotti A.iit, Rocchi A.iit, Kale D.D.iit, Martin C., Vazquez E., Bandiera T.iit, Ferroni S., Cesca F.iit, Benfenati F.iit

    An Increase in Membrane Cholesterol by Graphene Oxide Disrupts Calcium Homeostasis in Primary Astrocytes

    Small, vol. 15, (no. 15)
  • Bramini M.iit, Chiacchairetta M., Rocchi A., Vazquez E., Armirotti A.iit, Bandiera T.iit, Cesca F., Benfenati F.iit

    Graphene and the brain: interaction of graphene flakes with neurons and astrocytes

    Graphene 2019
  • Banchi E., Candotto Carniel F., Montagner A., Bosi S., Bramini M.iit, Crosera M., Leon V., Martin C., Pallavicini A., Vazquez E., Prato M., Tretiach M.

    Graphene-based materials do not impair physiology, gene expression and growth dynamics of the aeroterrestrial microalga Trebouxia gelatinosa

    Nanotoxicology, vol. 13, (no. 4), pp. 492-509
  • Bramini M.iit, Rocchi A.iit, Benfenati F.iit, Cesca F.iit

    Neuronal Cultures and Nanomaterials

    Advances in Neurobiology, vol. 22, pp. 51-79
  • 2018
  • Gambardella C., Morgana S., Bramini M.iit, Rotini A., Manfra L., Migliore L., Piazza V., Garaventa F., Faimali M.

    Ecotoxicological effects of polystyrene microbeads in a battery of marine organisms belonging to different trophic levels

    Marine Environmental Research, vol. 141, pp. 313-321
  • Bramini M., Cesca F., Benfenati F.iit

    Graphene and The Brain: Interaction of Graphene Flakes with Neurons, Astrocytes and Microglia

    Nanotox 2018
  • Cesca F.iit, Bramini M.iit, Benfenati F.iit

    Graphene and the Brain: the Neurobiology of the Interaction be-tween Graphene and Primary Neurons, Astrocytes and Microglia

    NanoMed 2018 / SMS 2018 / EGF 2018
  • Chiacchiaretta M.iit, Bramini M., Rocchi A.iit, Armirotti A.iit, Giordano E.iit, Vazquez E., Bandiera T.iit, Ferroni S., Cesca F.iit, Benfenati F.iit

    Graphene Oxide Upregulates the Homeostatic Functions of Primary Astrocytes and Modulates Astrocyte-to-Neuron Communication

    Nano Letters, vol. 18, (no. 9), pp. 5827-5838
  • Bramini M.iit, Alberini G.iit, Benfenati F.iit, Maragliano L.iit, Cesca F.iit

    Interactions Between 2D Graphene-Based Materials and the Nervous Tissue.

    Advanced 2D Materials – Characterization, Production and Applications, Publisher: SCIENCE PUBLISHERS (An Imprint of CRC Press/ Taylor & Francis Group)
  • Bramini M.iit, Alberini G.iit, Colombo E.iit, Chiacchiaretta M.iit, DiFrancesco M.L.iit, Maya-Vetencourt J.F.iit, Maragliano L.iit, Benfenati F.iit, Cesca F.iit

    Interfacing graphene-based materials with neural cells

    Frontiers in Systems Neuroscience, vol. 12
  • 2017
  • Piccini A., Castroflorio E.iit, Valente P., Guarnieri F.C., Aprile D., Michetti C.iit, Bramini M.iit, Giansante G., Pinto B.iit, Savardi A.iit, Cesca F.iit, Bachi A., Cattaneo A., Wren J.D., Fassio A.iit, Valtorta F., Benfenati F.iit, Giovedi S.

    APache Is an AP2-Interacting Protein Involved in Synaptic Vesicle Trafficking and Neuronal Development

    Cell Reports, vol. 21, (no. 12), pp. 3596-3611
  • Gambardella C., Morgana S., Ferrando S., Bramini M.iit, Piazza V., Costa E., Garaventa F., Faimali M.

    Effects of polystyrene microbeads in marine planktonic crustaceans

    Ecotoxicology and Environmental Safety, vol. 145, pp. 250-257
  • Ye D., Bramini M.iit, Hristov D.R., Wan S., Salvati A., Aberg C., Dawson K.A.

    Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers

    Beilstein Journal of Nanotechnology, vol. 8, (no. 1), pp. 1396-1406
  • Chiacchiaretta M.iit, Latifi S.iit, Bramini M.iit, Fadda M., Fassio A.iit, Benfenati F.iit, Cesca F.iit

    Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses

    Journal of Cell Science, vol. 130, (no. 8), pp. 1435-1449
  • 2016
  • Antognazza M.R.iit, Di Paolo M., Ghezzi D.iit, Mete M., Di Marco S., Maya-Vetencourt J.F.iit, Maccarone R., Desii A.iit, Di Fonzo F.iit, Bramini M.iit, Russo A., Laudato L.iit, Donelli I., Cilli M., Freddi G., Pertile G., Lanzani G.iit, Bisti S., Benfenati F.iit

    Characterization of a Polymer-Based, Fully Organic Prosthesis for Implantation into the Subretinal Space of the Rat

    Advanced healthcare materials, vol. 5, (no. 17), pp. 2271-2282
  • Bramini M.iit, Sacchetti S.iit, Armirotti A.iit, Rocchi A.iit, Vazquez E., Leon Castellanos V., Bandiera T.iit, Cesca F.iit, Benfenati F.iit

    Graphene Oxide Nanosheets Disrupt Lipid Composition, Ca2+ Homeostasis, and Synaptic Transmission in Primary Cortical Neurons

    ACS Nano, vol. 10, (no. 7), pp. 7154-7171
  • 2015
  • Gambardella C., Ferrando S., Morgana S., Gallus L., Ramoino P., Ravera S., Bramini M.iit, Diaspro A.iit, Faimali M., Falugi C.

    Exposure of Paracentrotus lividus male gametes to engineered nanoparticles affects skeletal bio-mineralization processes and larval plasticity

    Aquatic Toxicology, vol. 158, pp. 181-191
  • Gambardella C., Morgana S., Bari G.D., Ramoino P., Bramini M.iit, Diaspro A.iit, Falugi C., Faimali M.

    Multidisciplinary screening of toxicity induced by silica nanoparticles during sea urchin development

    Chemosphere, vol. 139, pp. 486-495
  • 2014
  • Zarschler K., Prapainop K., Mahon E., Rocks L., Bramini M., Kelly P.M., Stephan H., Dawson K.A.

    Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies

    Nanoscale, vol. 6, (no. 11), pp. 6046-6056
  • Bramini M., Ye D., Hallerbach A., Nic Raghnaill M., Salvati A., Aberg C., Dawson K.A.

    Imaging approach to mechanistic study of nanoparticle interactions with the blood-brain barrier

    ACS Nano, vol. 8, (no. 5), pp. 4304-4312
  • Raghnaill M.N., Bramini M., Ye D., Couraud P.-O., Romero I.A., Weksler B., Aberg C., Salvati A., Lynch I., Dawson K.A.

    Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

    The Analyst, vol. 139, (no. 5), pp. 923-930
  • 2013
  • Ye D., Raghnaill M.N., Bramini M., Mahon E., Aberg C., Salvati A., Dawson K.A.

    Nanoparticle accumulation and transcytosis in brain endothelial cell layers

    Nanoscale, vol. 5, (no. 22), pp. 11153-11165
  • 2012
  • Sterrenburg L., Gaszner B., Boerrigter J., Santbergen L., Bramini M., Roubos E.W., Peeters B.W., Kozicz T.

    Sex-dependent and differential responses to acute restraint stress of corticotropin-releasing factor-producing neurons in the rat paraventricular nucleus, central amygdala, and bed nucleus of the stria terminalis

    Journal of Neuroscience Research, vol. 90, (no. 1), pp. 179-192
  • 2011
  • Sterrenburg L., Gaszner B., Boerrigter J., Santbergen L., Bramini M., Elliott E., Chen A., Peeters B.W.M.M., Roubos E.W., Kozicz T.

    Chronic stress induces sex-specific alterations in methylation and expression of corticotropin-releasing factor gene in the rat

    PLoS ONE, vol. 6, (no. 11)
  • Ragnaill M.N., Brown M., Ye D., Bramini M., Callanan S., Lynch I., Dawson K.A.

    Internal benchmarking of a human blood-brain barrier cell model for screening of nanoparticle uptake and transcytosis

    European Journal of Pharmaceutics and Biopharmaceutics, vol. 77, (no. 3), pp. 360-367

Scientific Talks

  • 2019
  • Bramini M.iit, Chiacchairetta M., Rocchi A., Vazquez E., Armirotti A.iit, Bandiera T.iit, Cesca F., Benfenati F.iit

    Graphene and the brain: interaction of graphene flakes with neurons and astrocytes

  • 2018
  • Bramini M., Cesca F., Benfenati F.iit

    Graphene and The Brain: Interaction of Graphene Flakes with Neurons, Astrocytes and Microglia


1. Travel Award at Nanotox2018, 9th International Conference on Nanotoxicology, September 18th - 21st, Neuss (Germany), 2018

2. Best oral presentation at the 2013 Dublin Chemistry Graduate Programme 3rd Year PhD research showcase, Dublin, 30thMay 2013.

3. Best oral presentation award at the 2012 Irish Cytometry Society (ICyS) meeting held in NUI Galway on November 6thand 7th2012

4. European Materials Research Society Young Scientist Award in recognition of the outstanding oral contribution to the Symposium O at the 2011 E-Mrs Spring Meeting (Nice, France, 9th  - 13thMay 2011).