Assunta Merolla

Post Doc
Post Doc Researcher

Research Lines



Center for Synaptic Neuroscience (NSYN) Largo Rosanna Benzi 1,Torre D1, 16132, Genova
+39 010 5558357


I obtained a Bachelor Degree in Biology in 2013 at the University of Naples "Federico II". Then in 2016 I obtained a Master Degree summa cum laude in Molecular Biology at the University of Naples "Federico II". During my Master Degree thesis I worked at TIGEM (Telethon Institute of Genethics and Medicine) in Roman Polishchuck's laboratory where I started to study the lysosomal/autophagic system in a Wilson Disease cell model. In 2016 I started my PhD in "Neuroscience and Brain Technologies" in Fabio Benfenati's laboratory at the IIT @NSYN which I ended in March 2020.  

Selected Publications

1. Activation of autophagy, observed in liver tissues from patients with Wilson disease and from Atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis.

Polishchuk EV, Merolla A , Lichtmannegger J ,Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B ,Kroemer G, Zischka H, Polishchuk RS. Gastroenterology. 2018 Nov 16.


2Engineering REST-Specific Synthetic PUF Proteins to Control Neuronal Gene Expression: A Combined Experimental and Computational Study.

Criscuolo S, Gatti Iou M, Merolla A, Maragliano L, Cesca F, Benfenati F.  ACS Synth Biol. 2020 Aug 5.


3. Stability Studies of New Caged bis-deoxy-coelenterazine Derivatives and Their Potential Use as Cellular pH Probes.

 Giuliani G, Merolla A, Paolino M, Reale A, Saletti M, Blancafort L, Cappelli A, Benfenati F, Cesca F. Photochem Photobiol2020 Oct 23